Antonello Lorenzini

AFFILIATION

Department of Biomedical and Neuromotor Sciences. University of Bologna, School of Pharmacy, Biotechnology and Physical Education

PROFESSIONAL EXPERIENCE

1995-1999 Ph.D. in Biochemistry at the University of Bologna 1999-2005 Postdoctoral fellowship at the Lankenau Institute for Medical Research, Wynnewood, PA, USA. This is an empty line in HTML. 2005-2006 Role of Scientist at the Lankenau Institute for Medical Research, Wynnewood, PA, USA. This is an empty line in HTML. 2006-2007 Role of Research Associate at Drexel University College of Medicine, Philadelphia, PA, USA. This is an empty line in HTML. 2007-Present. Adjunct Professor of Nutrition This is an empty line in HTML. 2013-Present Role of "Specialty Chief Editor" for the journal Frontiers in Endocrinology, for the section Endocrinology of Aging.

RESEARCH INTEREST

His research has focused on the cellular mechanisms that ensure longevity and on the extracellular and intracellular signals that regulate them. In Dr. Cristofalo's laboratory in Philadelphia, he dedicated himself to the study of intracellular signals that regulate cell proliferation and senescence. He also analyzed the different replicative capacities of cells from various mammals, evaluating their correlation with the species' longevity. With Dr. Sell at Drexel University, he studied the endocrine regulation of longevity, aiming to separate the influence on longevity of the hormones GH and IGF-1. Currently, at the Department of Biomedical and Neuromotor Sciences at the University of Bologna, he studies how signals generated in the cell after DNA damage influence the progression of the cell cycle. For this purpose, he uses a comparative approach using a cell bank composed of samples from mammals of different longevities.

RECENT SELECTED PUBLICATIONS

1. How much should we weigh for a long and healthy life span? The need of reconciling caloric restriction versus longevity with body mass index versus mortality data. Lorenzini A. Front Endocrinol (Lausanne). 2014 Jul 30;5:121. doi: 10.3389/fendo.2014.00121. eCollection 2014. Review.
2. Topi che producono livelli ridotti di fattore di crescita simile all'insulina di tipo 1 mostrano un aumento della durata massima, ma non media, della vita. Lorenzini A, Salmon AB, Lerner C, Torres C, Ikeno Y, Motch S, McCarter R, Sell C. J Gerontol A Biol Sci Med Sci. 2014 Apr;69(4):410-9. Doi10.1093/Gerona/glt108. Epub 2013 Jul 20.
3. Relationship of spindle assembly checkpoint fidelity to species body mass, lifespan, and developmental rate. Lorenzini A, Fink LS, Stamato T, Torres C, Sell C. Aging (Albany NY). 2011 Dec;3(12):1206-12.PMID:22201071 [PubMed - in process] Free Article
4. The disposable soma theory revisited: Time as a resource in the theories of aging. Lorenzini A, Stamato T, Sell C. Cell Cycle. 2011 Nov 15;10(22):3853-6. Epub 2011 Nov 15. PMID:22071624
5. 53BP1 contributes to a robust genomic stability in human fibroblasts. Fink LS, Roell M, Caiazza E, Lerner C, Stamato T, Hrelia S, Lorenzini A, Sell C. Aging (Albany NY). 2011 Sep;3(9):836-45.PMID:21931182 Published in New York State, USA